Juventus under caretaker manager Massimo Brambilla host Udinese with Kenan Yildiz, Dusan Vlahovic and Lois Openda upfront, plus some big midfield changes.
It kicks off at the Allianz Juventus Stadium in Turin at 17.30 GMT.
You can follow all the build-up and action as it happens from today’s six Serie A games on the Liveblog.
The Bianconeri pulled the plug on coach Igor Tudor on Monday after three consecutive defeats in all competition, and four games without scoring a goal.
They are on a seven-game winless streak and expected to appoint new coach Luciano Spalletti tomorrow.
Meanwhile, Next Gen boss Brambilla is the caretaker for this midweek round and he tries to keep changes to a minimum, maintaining the three-man defence.
Khephren Thuram is out of the squad with a calf issue, joining Gleison Bremer, Juan Cabal, Arek Milik and Carlo Pinsoglio in the stands.
In a bid to end their goal drought, Kenan Yildiz returns to the XI after a knee problem saw him initially rested for the loss to Lazio.
Vlahovic is again with a strike partner, but this time it is Openda rather than misfiring Jonathan David.
Teun Koopmeiners is dropped and Filip Kostic steps in on the left wing.
Udinese are unbeaten in three and coming off a chaotic 3-2 victory over Lecce.
Thomas Kristensen, Iker Bravo and Alessandro Nunziante are on the treatment table, while Oumar Solet is not at 100 per cent either, but still plays.
Nicolò Zaniolo is again the partner to Keinan Davis upfront, with Arthur Atta in impressive form too.
Goalkeeper Maduka Okoye starts his third game of the season after a lengthy ban for betting irregularities, and has looked rusty.
Juventus vs. Udinese line-ups
Juventus: Di Gregorio; Kalulu, Gatti, Kelly; Cambiaso, Locatelli, McKennie, Kostic; Yildiz; Openda, Vlahovic
Udinese: Okoye; Goglichidze, Kabasele, Solet; Ehizibue, Piotrowski, Karlstrom, Atta, Kamara; Zaniolo, Davis
Player statistic
| 3' |  |
Saba Goglichidze | ||
| Dusan Vlahovic |  |
5' | ||
| 45+3' | |
Jakub Piotrowski | ||
| 45+1' |  |
Nicolò Zaniolo |
| Federico Gatti (Assist: Andrea Cambiaso) |
|
67' | ||
| 79' | |
Sandi Lovric | ||
| 82' | |
Lennon Miller | ||
| Kenan Yıldız | |
90+6' | ||
| Michele Di Gregorio | |
90' |
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